Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice
نویسندگان
چکیده
منابع مشابه
Insulitis in NOD Mice
The active form of vitamin D, 1,25(OH)2D3, can prevent various forms of experimentally induced autoimmune disorders. The aim of this study was to confirm these findings in NOD mice that spontaneously develop an autoimmune type of diabetes mellitus. Therefore, the effect of a long-term 1,25(OH)2D3 treatment on the incidence of insulitis, the histological lesion preceding diabetes, was studied. F...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2009
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-009-1626-y